田所医師が執筆した論文「高校生の生活習慣病健診について」が
『Journal of Atherosclerosis and Thrombosis』に掲載されました。
皆様 猛暑の候、いかがお過ごしでしょうか。 大変遅くなりましたが、小象の会で行いました高校生の健診の論文を何とか仕上げることができました。 現在Pub Medで読むことができます。 皆様のご尽力に心より感謝申し上げます。 （田所）
| J Atheroscler Thromb. 2010 Jun 30;17(6):546-57. Epub 2010 Jun 16. Visceral fat accumulation in Japanese high school students and related atherosclerotic risk factors. Tadokoro N, Shinomiya M, Yoshinaga M, Takahashi H, Matsuoka K, Miyashita Y, Nakamura M, Kuribayashi N. Watanabe Clinic, Funabashi, Chiba 273-0003, Japan.Abstract AIM: To investigate the factors that influence visceral fat accumulation in adolescence, we performed a medical examination of high school students and assessed abdominal fat thickness and fatty change of the liver. METHODS: A cohort of 374 Japanese high school students aged 15-16 years (193 boys and 181 girls) in public high schools in Chiba prefecture were enrolled. Anthropometric parameters, blood cell count, blood chemistry and adipocytokine levels were measured. Preperitoneal fat thickness (PFT) and echoic contrast of the liver were measured by ultrasonography. RESULTS: Anthropometric parameters, systolic blood pressure, blood cell count, ALT, AST, FBS, gamma-GTP, HDL-C, LpL, UA, adiponectin, resistin and leptin levels differed between sexes. Multivariate regression analysis revealed that leptin was the most appropriate marker for PFT in both sexes (p<0.0001). Visceral obesity, categorized as PFT exceeding 8 mm, was observed in 9.6% of all students. Boys with visceral obesity showed apparent liver dysfunction, hyperlipidemia, hyperinsulinemia, and high leptin and low adiponectin levels. Overall, 16.6% of boys and 30.4% of girls showed hepatorenal echo contrast positivity. Boys with visceral obesity and fatty liver had more risk factors for atherosclerosis. CONCLUSIONS: Physical examination of high school students is important for early detection of atherosclerosis. |
